Brett_Morrison_Research_ImageRole of monocarboxylate transporters in oligodendrocytes and peripheral nerves.

Investigate basic mechanisms of cellular metabolism in the nervous system, neurodegeneration in amyotrophic lateral sclerosis (ALS), and regeneration of peripheral nerves using genetic tools to alter expression of monocarboxylate transporters.

Recent Publications

  1. Morrison, B.M., Lachey, J.L., Warsing, L.C., Ting, B.L., Pullen, A.E., Underwood, K.W., Kumar R., Sako, D., Grinberg A., Wong, V., Colantuoni, E., Seehra, J.S., Wagner K.R. (2009) A soluble activin type IIB receptor improves function in a mouse model of amyotrophic lateral sclerosis. Exp. Neurol. 217: 258-68.
  2. Lee, Y.*, Morrison, B.M.*, Li, Y., Lengacher, S., Farah, M.H., Hoffman, P.N., Liu, Y., Tsingalia, A., Jin, L., Zhang, P-W., Pellerin, L., Magistretti, P.J., Rothstein, J.D. (2012) Oligodendroglia metabolically support axons and contribute to neurodegeneration. Nature 487 (7408): 443-448.
    *Authors contributed equally to this work
  3. Morrison, B.M., Lee, Y., Rothstein, J.D. Oligodendroglia metabolically support axons and maintain structural integrity. Trends Cell Biol. 2013; 23 (12): 644-651.