Differentiation of iPSCs into astrocytes, motor neurons and cortical neurons
Description of your project: Differentiate and characterize cortical neurons, motor neurons and astrocytes generated from ALS patient induced Pluripotent Stem (iPS) cells for the purpose of disease modeling, mechanistic studies, and drug discovery. Maintain and expand iPSCs for future experiments.
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- Marshall LJ, Ferenczy MW, Daley EL, Jensen PN, Ryschkewitsch CF, Major EO. Lymphocyte Gene Expression and JC Virus Noncoding Control Region Sequences Are Linked with the Risk of Progressive Multifocal Leukoencephalopathy. J Virol. May 2014.